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. 2014 Jun 11;9(6):e99788. doi: 10.1371/journal.pone.0099788

Table 1. Characteristics of RTB-specific VHHs and mAbs used in this study.

VHH/mAbs GenBanka Length (AA) Verob THP-1 Prec THP-1 Postc Protection
TFTB-1d NA NA ND ND ND
24B11d NA NA 1.2 0.25 0.25 +
RTB-B7 KF746034 132 1.5 0.25 1.4
RTB-D12 KF746031 130 330
RTB-D8 KF746036 124 330
RTA-G12 KF746020 137 ND ND ND
a

GenBank accession numbers; bVero cytotoxicity assay performed as described in Materials and Methods; value shown are in nM; cPre-bound and post-bound THP-1 cytotoxicity assays performed in Materials and Methods; values shown are in nM. dAnti-RTB mAbs previously characterized in [26], [29]. Abbreviations: ND, not determined; NA, not applicable.