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. 2014 Jun 11;9(6):e100095. doi: 10.1371/journal.pone.0100095

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© 2014 Lv et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A–B, Caffeine (10 mM, 60 s) induced [Ca²⁺]_i responses in: (A) normal Ringer’s solution (control), and (B) in the presence of ryanodine (2.5 µM). C, The average number of Ca²⁺ transients induced by caffeine (10 mM, 60 s) in the control group and the ryanodine group. * denotes statistical significance of p<0.05 with independent-samples t test.