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. 2014 Jun 11;9(6):e98227. doi: 10.1371/journal.pone.0098227

Table 3. Metabolite relative levels in serum patients with and without microalbuminuria.

Metabolites ppm Nomicroalbuminuria Microalbuminuria P-value
Cholesterol 0.60–0.75 3.17±0.44 2.95±0.44 <0,001
Lipid (–CH3) 0.80–0.90 7.26±0.39 7.35±0.47 0,002
Isoleucine + Leucine 0.92–0.97 2.41±0.10 2.31±0.15 <0,001
Isoleucine + valine 0.98–1.00 0.82±0.04 0.78±0.06 <0,001
Valine 1.03–1.05 0.65±0.03 0.61±0.05 <0,001
Lipids (-CH2-)n 1.20–1.32 12.59±2.08 14.78±2.91 <0,001
Lactate 1.32–1.35 1.83±0.38 2.09±0.45 <0,001
Alanine 1.46–1.49 1.12±0.06 1.05±0.08 <0,001
Lipids (βCH2) 1.55–1.60 1.67±0.16 1.82±0.23 <0,001
Isoleucine 1.92–1.97 1.52±0.07 1.44±0.09 <0,001
4-aminobutyrate + ( = CH-CH2-CH2-) 1.98–2.03 2.31±0.18 2.48±0.25 <0,001
N-acetylglutamine 2.10–2.15 1.17±0.07 1.10±0.09 <0,001
Pyruvate 2.34–2.38 0.62±0.05 0.58±0.06 <0,001
3-OH-isovalerate 2.34–2.41 1.05±0.08 0.96±0.09 <0,001
Glutamine 2.43–2.47 0.56±0.04 0.51±0.06 <0,001
Dimetylamine 2.65–2.80 2.03±0.11 1.99±0.13 <0,001
Trimethylamine 2.90–2.95 0.59±0.05 0.54±0.06 <0,001
Albumin 2.95–3.00 0.72±0.06 0.66±0.07 <0,001
Creatine + creatineP 3.02–3.05 0.46±0.03 0.43±0.05 <0,001
Choline 3.18–3.20 0.46±0.03 0.43±0.05 <0,001
O-phosphocholine 3.21–3.22 1.02±0.42 0.92±0.37 <0,001
Proline 3.32–3.37 0.30±0.04 0.28±0.04 <0,001
Glucose 3.45–3.48 0.35±0.07 0.38±0.11 <0,001
Leucine 3.68–3.72 0.60±0.07 0.61±0.10 0,015
Creatine-P 3.93–3.97 0.61±0.05 0.58±0.08 <0,001
Creatinine 4.03–4.08 0.72±0.05 0.75±0.13 <0,001