Table 3. Metabolite relative levels in serum patients with and without microalbuminuria.
Metabolites | ppm | Nomicroalbuminuria | Microalbuminuria | P-value |
Cholesterol | 0.60–0.75 | 3.17±0.44 | 2.95±0.44 | <0,001 |
Lipid (–CH3) | 0.80–0.90 | 7.26±0.39 | 7.35±0.47 | 0,002 |
Isoleucine + Leucine | 0.92–0.97 | 2.41±0.10 | 2.31±0.15 | <0,001 |
Isoleucine + valine | 0.98–1.00 | 0.82±0.04 | 0.78±0.06 | <0,001 |
Valine | 1.03–1.05 | 0.65±0.03 | 0.61±0.05 | <0,001 |
Lipids (-CH2-)n | 1.20–1.32 | 12.59±2.08 | 14.78±2.91 | <0,001 |
Lactate | 1.32–1.35 | 1.83±0.38 | 2.09±0.45 | <0,001 |
Alanine | 1.46–1.49 | 1.12±0.06 | 1.05±0.08 | <0,001 |
Lipids (βCH2) | 1.55–1.60 | 1.67±0.16 | 1.82±0.23 | <0,001 |
Isoleucine | 1.92–1.97 | 1.52±0.07 | 1.44±0.09 | <0,001 |
4-aminobutyrate + ( = CH-CH2-CH2-) | 1.98–2.03 | 2.31±0.18 | 2.48±0.25 | <0,001 |
N-acetylglutamine | 2.10–2.15 | 1.17±0.07 | 1.10±0.09 | <0,001 |
Pyruvate | 2.34–2.38 | 0.62±0.05 | 0.58±0.06 | <0,001 |
3-OH-isovalerate | 2.34–2.41 | 1.05±0.08 | 0.96±0.09 | <0,001 |
Glutamine | 2.43–2.47 | 0.56±0.04 | 0.51±0.06 | <0,001 |
Dimetylamine | 2.65–2.80 | 2.03±0.11 | 1.99±0.13 | <0,001 |
Trimethylamine | 2.90–2.95 | 0.59±0.05 | 0.54±0.06 | <0,001 |
Albumin | 2.95–3.00 | 0.72±0.06 | 0.66±0.07 | <0,001 |
Creatine + creatineP | 3.02–3.05 | 0.46±0.03 | 0.43±0.05 | <0,001 |
Choline | 3.18–3.20 | 0.46±0.03 | 0.43±0.05 | <0,001 |
O-phosphocholine | 3.21–3.22 | 1.02±0.42 | 0.92±0.37 | <0,001 |
Proline | 3.32–3.37 | 0.30±0.04 | 0.28±0.04 | <0,001 |
Glucose | 3.45–3.48 | 0.35±0.07 | 0.38±0.11 | <0,001 |
Leucine | 3.68–3.72 | 0.60±0.07 | 0.61±0.10 | 0,015 |
Creatine-P | 3.93–3.97 | 0.61±0.05 | 0.58±0.08 | <0,001 |
Creatinine | 4.03–4.08 | 0.72±0.05 | 0.75±0.13 | <0,001 |