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. Author manuscript; available in PMC: 2014 Jun 11.
Published in final edited form as: Bioconjug Chem. 2008 Aug 19;19(9):1813–1821. doi: 10.1021/bc800154f

Figure 1.

Figure 1

pH dependent release of doxorubicin from the polyglutamic acid-H2009.1 peptide conjugate. Polyglutamic acid-H2009.1-doxorubicin conjugate was dissolved in aqueous buffer at pH 7.0, pH 5.6, or pH 4.0 and incubated at 37 °C. At the indicated times, aliquots were removed and the ratio of unconjugated to conjugated doxorubicin was assessed by reverse phase HPLC on an analytical C18 column.