Table 2.
Odds ratios (OR) and 95% confidence intervals (CI) for congenital heart defects by categories of body mass index (BMI) among 121815 pregnancies in the Consortium on Safe Labor
| Total (n) | Cases (n) | Crude | Multivariable * | |||
|---|---|---|---|---|---|---|
| OR (95%CI) | P value | OR (95% CI) | P value | |||
| p-value for trend test=<.001 | p-value for trend test=<.001 | |||||
| Underweight | ||||||
| <18.5kg/m2 | 6268 | 72 | 1.11 (0.87–1.42) | 0.405 | 1.08 (0.85–1.38) | 0.529 |
| Normal Weight | ||||||
| 18.5–<25 kg/m2 | 62813 | 651 | 1.00 (ref) | n/a | 1.00 (ref) | n/a |
| Overweight | ||||||
| 25–<30 kg/m2 | 28871 | 352 | 1.18 (1.03–1.34) | 0.014 | 1.15 (1.01–1.32) | 0.033 |
| Obese | ||||||
| 30–<40 kg/m2 | 19718 | 255 | 1.25 (1.08–1.45) | 0.003 | 1.24 (1.07–1.44) | 0.005 |
| Morbidly Obese | ||||||
| 40+kg/m2 | 4145 | 58 | 1.36 (1.03–1.78) | 0.028 | 1.34 (1.02–1.76) | 0.036 |
| All Obese | ||||||
| 30+kg/m2 | 23863 | 313 | 1.27 (1.11, 1.45) | 0.001 | 1.26 (1.09–1.44) | 0.001 |
*
adjusted for site, age, race, insurance, maternal smoking