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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Neurobiol Learn Mem. 2013 Dec 27;113:25–34. doi: 10.1016/j.nlm.2013.12.009

Figure 1. Effects of DCS delivered to the hippocampus immediately before or after extinction.

Figure 1

(A) DCS (black symbols; n=16) or saline (open symbols; n=18) was administered into the hippocampus immediately prior to the extinction session. Mean % time freezing is presented in 3-min time blocks during extinction (Ext), a test one day (1d), four days (4d), or 14 days (14d) after extinction, as well as one day after a reconditioning session (RC). Each session was 12 min. (B) Freezing behavior in mice categorized as Extinguishers following pre-extinction session DCS (n=5) or saline (n=6). (C) Freezing behavior in mice categorized as Non-Extinguishers following pre-extinction session DCS (n=5) or saline (n=6). (D) Freezing behavior in all mice that received DCS (n=22) or saline (n=19) immediately after the extinction session (Post-Ext). (E) Freezing behavior in mice categorized as Extinguishers following post-extinction session DCS (n=8) or saline (n=7). (F) Freezing behavior in mice categorized as Non-Extinguishers following post-extinction session DCS (n=7) or saline (n=6). Error bars indicate standard error of the mean.