Equation
of state of the helix in the membrane. (A) The dependence
of α on Peff and L, for three different ω values. The tilt angle (α) was
calculated using the second line of eq 6 in
the range 15 Å < Peff < 50
Å and 20 Å < L < 40 Å, using
the appropriate limitations on L and Peff (i.e., (P – L) < 5 Å and Peff ≥ 0.8L). Clearly, the dependence of α on ω is marginally
weak. As expected, α decreases with L and increases
with Peff. (B) The dependence
of α on Peff/L for
ω = 0.075 kT/Å2. The tilt angle
α increases with an increase in Peff at the same L (symbols with the same color). Interestingly,
there is a linear relation between α and the Peff-to-L ratio at constant (Peff – L).