Table 1. Phenomenology, Treatment, and Frequency of PBT for the four patients.
Patient 1 | Patient 2 | Patient 3 | Patient 4 | |
---|---|---|---|---|
Gender | male | male | male | female |
Age in years | 62 | 54 | 48 | 50 |
Age when starting to play the violin | 8 | 12 | 4 | 13 |
Age at onset of PBT | 46 | 43 | 40 | 43 |
Tremor duration in years | 16 | 11 | 8 | 7 |
Unilateral right tremor | y | y | y | y |
Previous trauma | y | n | n | y |
Spreading of tremor | y | Y | y | n |
Postural tremor | n | n | n | y |
Rest tremor | n | n | n | n |
Medication | Prop, Thx, Gabap, Topi, Prim | Prim, Prop | Prim, Prop | Prop |
Botulinum toxin | y | n | y | n |
Ethanol responsive | y | y | little | n |
Family history for tremor | y | y | n | n |
Deep brain stimulation | n | n | n | n |
Tremor frequency GM/OS | 5.9/6.7 Hz | 4.7/4.9 Hz | 6.5/5.5 Hz | 6.1/5.7 Hz |
Gabap, Gabapentin; GM, G Major Scale Condition; PBT, Primary Bowing Tremor; OS, Open-string Condition; Prim, Primidone; Prop, Propranolol; Thx, Trihexyphenidyl; Topi, Topiramat.