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. 2014 Feb 9;133(7):869–881. doi: 10.1007/s00439-014-1427-3

Table 1.

Replication cohorts

Iowa LI Colorado RD Italy RD
Cohort-type Case–control Family-based Family-based
Number of subjects 428 1,188 878
Number of families N/A 292 304
Disorder LI RD RD
Analysis SVS TDT (PLINK) TDT (PLINK)
Association conditioned on: Case–control status Case–control status, discriminant score Case–control status
Case status determined by: Composite score on language measures Composite discriminant score on reading tasks Text-, single-word, or non-word reading tasks