Table 6.

Replication of genetic associations in the Iowa, Italian, and Colorado cohorts

Marker	Gene	Iowa case control		Italy case control		Colorado case control		Colorado discriminant score
		OR	p	OR	p	OR	p	Slope	p
rs2328791	N/A	1.0	0.813	1.0	1.000	0.9	0.646	0.087	0.447
rs33914824a	DCDC2	2.2	0.034	0.9	0.768	1.1	0.847	0.023	0.934
rs807694a	DCDC2	1.9	0.028	0.9	0.786	0.9	0.853	−0.025	0.919
rs707864a	DCDC2	1.6	0.017	1.0	0.840	1.2	0.446	−0.246	0.101
rs10456301a	DCDC2	0.9	0.553	1.1	0.811	1.5	0.289	0.221	0.162
rs16889066a	DCDC2	1.2	0.517	1.0	0.884	1.2	0.622	−0.304	0.150
rs9379651a	DCDC2	1.1	0.602	1.3	0.225	0.6	0.059	0.205	0.141
rs2817201	KIAA0319	1.1	0.733	1.2	0.129	1.0	1.000	0.034	0.787
rs9295626	KIAA0319	1.1	0.579	0.6	0.0055	1.0	0.823	−0.158	0.169
rs10456309	KIAA0319	0.5	0.073	0.7	0.189	0.4	0.206	0.628	0.0133
rs4576240	KIAA0319	1.1	0.825	1.9	0.0027	1.1	0.862	−0.052	0.754
rs17307478	KIAA0319	1.0	0.996	1.3	0.292	0.8	0.555	0.039	0.803
rs9356939	KIAA0319	4.0	0.018	0.8	0.069	1.3	0.151	−0.116	0.254
rs7763790	KIAA0319	1.0	0.831	1.1	0.627	1.4	0.163	0.014	0.910
rs6456621	KIAA0319	2.2	0.019	1.6	0.405	1.8	0.366	−0.458	0.104
rs3756821	KIAA0319	1.2	0.278	1.0	0.842	1.2	0.327	−0.033	0.734
rs1883593	KIAA0319	1.3	0.169	1.6	0.0052	1.3	0.239	−0.108	0.395
rs3212236	KIAA0319	1.0	0.883	1.1	0.496	0.9	0.745	−0.124	0.319
rs2294691	TDP2	1.1	0.779	1.9	0.0578	1.4	0.491	−0.290	0.247
rs3777663	ACOT13	0.7	0.016	0.6	0.0052	1.0	0.908	0.101	0.345
rs3756814	C6orf62	0.7	0.005	0.7	0.023	0.9	0.600	−0.003	0.980
rs6931809	C6orf62	1.4	0.023	1.4	0.017	1.2	0.491	−0.096	0.382
rs6916186	C6orf62	0.9	0.757	1.2	0.413	1.2	0.547	0.112	0.490
rs6933328	C6orf62	0.9	0.612	0.9	0.613	1.0	0.827	0.215	0.0515
rs17491647	C6orf62	0.8	0.155	0.7	0.104	1.0	0.901	0.042	0.709
rs9348646	FAM65B	0.9	0.358	1.1	0.535	1.4	0.144	−0.415	0.00051
rs1562422	CMAHP	1.0	0.793	1.0	0.796	0.6	0.093	−0.030	0.840

^aThese markers are part of the six-marker risk haplotype in DCDC2 fully discussed in Powers et al. (2013)

Bold denotes nominally associated markers