Fig. 5.

Axial diffusivity decreases in the ventrolateral white matter and the posterior area of the dorsal white matter in the lumbar spinal cord with increasing disease severity in EAE mice. Axial diffusivity maps of the spinal cords (segment L2) of EAE animals obtained using in vivo DTI are shown where clinical scores (CS) range from 0 (least severe) to 4 (most severe). Areas with the highest axial diffusivity values are shown in red, while areas with the lowest axial diffusivity values are shown in green and blue.

(Adapted from Budde et al. (2009).)