Fig. 7.

Mice with TMEV develop ventricular enlargement concurrently with disease progression as seen using T₂-weighted imaging with 3D MRI datasets. (A) shows the brain of a normal mouse where no ventricular enlargement is seen over the span of 12 months. (B) shows the brain of a mouse with TMEV where ventricular enlargement can be seen on both the right and left sides, which gets progressively worse the longer the animal has the disease.

(Adapted from Pirko et al. (2011).)