Fig. 8.
Cuprizone-treated mice have elevated T2* values and significantly reduced-grey–white matter contrast in the cortex and corpus callosum compared to control mice. (A) shows T2* maps for control mice obtained ex vivo. T2* values are shorter (darker on T2* maps) in the cortex and corpus callosum of controls compared to images shown in (B) which are the T2* maps for cuprizone-treated mice obtained ex vivo. Also, grey–white matter contrast is reduced in cuprizone-treated mice compared to control mice.
(Adapted from Lee et al. (2012).)