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Typical T2 distribution of UBO (red) and cNAWM (blue). Red and blue vertical dashed lines indicate the IEW-gmT2 of UBO and cNAWM, respectively. The intra- and extracellular water (IEW) peak in the UBO shows a shift towards longer T2 times as illustrated by the red arrows. Vertical dashed lines in black indicate the integration interval for the IEW peak. Left: cerebral peduncle; middle: splenium of corpus callosum; right: cerebellar white matter.
