Table 3.
Summary of ROI resultsa.
| DTI metric | Group comparison | Region | T-statistic | p(FWE)b | p(uncorr)c |
|---|---|---|---|---|---|
| FA | Aβ + > Aβ − | Medial cingulum (R) | 4.80 | 0.003 | 0.000 |
| Fornix (L) | 4.16 | 0.030 | 0.000 | ||
| Posterior cingulum (R) | 4.10 | 0.036 | 0.000 | ||
| Fornix (R) | 3.81 | 0.092 | 0.000 | ||
| Hippocampal cingulum (L) | 3.69 | 0.131 | 0.000 | ||
| Medial cingulum (L) | 3.65 | 0.144 | 0.000 | ||
| Posterior cingulum (L) | 3.55 | 0.193 | 0.000 | ||
| Aβi > Aβ − | Medial cingulum (R) | 4.56 | 0.007 | 0.000 | |
| Posterior cingulum (R) | 4.45 | 0.011 | 0.000 | ||
| Medial cingulum (L) | 3.62 | 0.158 | 0.000 |
a
Atrophy correction did not change the overall pattern of results. Atrophy-corrected data are presented in Inline Supplementary Table S1.
b
FWE = family wise error correction for multiple comparisons.
c
p(uncorr) = p-value uncorrected for multiple comparisons.