Table 1.
Top 16 genes differentially expressed between males and females in the Nigerian data
| Ensembl ID | Symbol | Chr | logFC | AveExpr | t | P value | FDR | B |
|---|---|---|---|---|---|---|---|---|
| ENSG00000229807 |
XIST |
X |
-9.815 |
3.8084 |
-36.4 |
7.03e-48 |
1.19e-43 |
74.8 |
| ENSG00000099749 |
CYorf15A |
Y |
4.251 |
0.3146 |
28.3 |
1.25e-40 |
1.05e-36 |
68.2 |
| ENSG00000157828 |
RPS4Y2 |
Y |
3.281 |
3.3081 |
26.5 |
9.38e-39 |
5.27e-35 |
72.6 |
| ENSG00000233864 |
TTTY15 |
Y |
4.897 |
-0.5538 |
25.9 |
4.31e-38 |
1.82e-34 |
64.0 |
| ENSG00000131002 |
CYorf15B |
Y |
5.440 |
-0.1710 |
23.2 |
4.81e-35 |
1.62e-31 |
60.0 |
| ENSG00000198692 |
EIF1AY |
Y |
2.398 |
2.6806 |
20.5 |
1.09e-31 |
3.07e-28 |
58.6 |
| ENSG00000165246 |
NLGN4Y |
Y |
5.330 |
-0.4916 |
19.7 |
1.26e-30 |
3.03e-27 |
52.4 |
| ENSG00000213318 |
RP11-331F4.1 |
16 |
4.293 |
2.2654 |
19.3 |
4.44e-30 |
9.34e-27 |
54.1 |
| ENSG00000129824 |
RPS4Y1 |
Y |
2.781 |
4.7118 |
17.6 |
9.28e-28 |
1.74e-24 |
51.5 |
| ENSG00000183878 |
UTY |
Y |
1.878 |
2.7430 |
16.6 |
2.88e-26 |
4.85e-23 |
47.7 |
| ENSG00000012817 |
KDM5D |
Y |
1.470 |
4.7046 |
14.9 |
1.45e-23 |
2.22e-20 |
42.6 |
| ENSG00000146938 |
NLGN4X |
X |
4.472 |
-0.7801 |
14.8 |
2.09e-23 |
2.94e-20 |
38.9 |
| ENSG00000243209 |
AC010889.1 |
Y |
2.528 |
-0.0179 |
14.5 |
5.48e-23 |
7.11e-20 |
37.9 |
| ENSG00000067048 |
DDX3Y |
Y |
1.671 |
5.3077 |
13.4 |
3.05e-21 |
3.67e-18 |
37.5 |
| ENSG00000006757 |
PNPLA4 |
X |
-0.988 |
2.5341 |
-10.4 |
4.78e-16 |
5.38e-13 |
25.7 |
| ENSG00000232928 | RP13-204A15.4 | X | 1.434 | 3.2506 | 10.3 | 1.02e-15 | 1.08e-12 | 25.2 |
The table shows output from the limma topTable function. As well as gene ID and symbol, columns give chromosome location (Chr), log2-fold-change (logFC), average log2 expression (AveExpr), moderated t, P value, false discovery rate and B-statistic for each gene. The B-statistic is the posterior log-odds of differential expression.