Table 2.
In- cis miRNAs confirmed in the replication cohort
| miRNA | MIMAT id | Chromosomal location (hg19) | Replicated aberration type |
|---|---|---|---|
| let-7e-3p |
MIMAT0004485 |
19q13.41 |
Hypermethylation |
| miR-125a-5p |
MIMAT0000443 |
19q13.41 |
Hypermethylation |
| miR-130b-3p |
MIMAT0000691 |
22q11.21 |
Gain |
| miR-135b-5p |
MIMAT0000758 |
1q32.1 |
Hypomethylation |
| miR-141-3p |
MIMAT0000432 |
12p13.31 |
Gain |
| miR-142-3p |
MIMAT0000434 |
17q22 |
Hypomethylation |
| miR-142-5p |
MIMAT0000433 |
17q22 |
Hypomethylation |
| miR-148a-3p |
MIMAT0000243 |
7p15.2 |
Hypermethylation |
| miR-148a-5p |
MIMAT0004549 |
7p15.2 |
Hypermethylation |
| miR-148b-3p |
MIMAT0000759 |
12q13.13 |
Gain |
| miR-151a-3p |
MIMAT0000757 |
8q24.3 |
Gain |
| miR-151a-5p |
MIMAT0004697 |
8q24.3 |
Gain |
| miR-15b-3p |
MIMAT0004586 |
3q25.33 |
Gain and hypomethylation |
| miR-16-2-3p |
MIMAT0004518 |
3q25.33 |
Hypomethylation |
| miR-17-3p |
MIMAT0000071 |
13q31.3 |
Hypomethylation |
| miR-17-5p |
MIMAT0000070 |
13q31.3 |
Hypomethylation |
| miR-182-3p |
MIMAT0000260 |
7q32.2 |
Gain |
| miR-186-5p |
MIMAT0000456 |
1p31.1 |
Gain and loss |
| miR-190b |
MIMAT0004929 |
1q21.3 |
Hypomethylation |
| miR-193b-3p |
MIMAT0002819 |
16p13.12 |
Gain |
| miR-19a-3p |
MIMAT0000073 |
13q31.3 |
Hypomethylation |
| miR-19b-3p |
MIMAT0000074 |
13q31.3 |
Hypomethylation |
| miR-200c-3p |
MIMAT0000617 |
12p13.31 |
Gain and hypomethylation |
| miR-200c-5p |
MIMAT0004657 |
12p13.31 |
Gain |
| miR-205-5p |
MIMAT0000266 |
1q32.2 |
Hypomethylation |
| miR-21-3p |
MIMAT0004494 |
17q23.1 |
Gain |
| miR-219-5p |
MIMAT0000276 |
6p21.32 |
Gain |
| miR-29b-2-5p |
MIMAT0004515 |
1q32.2 |
Gain |
| miR-301a-3p |
MIMAT0000688 |
17q22 |
Gain |
| miR-30b-3p |
MIMAT0004589 |
8q24.22 |
Gain |
| miR-30c-2-3p |
MIMAT0004550 |
6q13 |
Hypomethylation |
| miR-30c-5p |
MIMAT0000244 |
6q13 |
Hypomethylation |
| miR-30d-3p |
MIMAT0004551 |
8q24.22 |
Gain |
| miR-30d-5p |
MIMAT0000245 |
8q24.22 |
Gain |
| miR-423-3p |
MIMAT0001340 |
17q11.2 |
Gain |
| miR-423-5p |
MIMAT0004748 |
17q11.2 |
Gain |
| miR-454-3p |
MIMAT0003885 |
17q22 |
Gain |
| miR-484 |
MIMAT0002174 |
16p13.11 |
Gain |
| miR-93-3p |
MIMAT0004509 |
7q22.1 |
Gain |
| miR-93-5p |
MIMAT0000093 |
7q22.1 |
Gain |
| miR-9-3p | MIMAT0000442 | 15q26.1 | Gain |