Table 2.
Assessment of renal variables before and after 24 h of aminophylline.
| Variable | Baseline value | 24-h value | p Value |
|---|---|---|---|
| ENTIRE COHORT (n = 34) | |||
| Urine outputa | 3.6 ± 0.4 (3.5 [2.0, 5.0]) | 4.7 ± 0.5 (4.2 [2.7, 5.6]) | 0.0004 |
| BUNb | 20.7 ± 3.1 (13.5 [8.0, 27.0]) | 22.5 ± 3.9 (15.0 [9.0, 25.0]) | 0.16 |
| Creatinineb | 0.70 ± 0.15 (0.38 [0.27, 0.55]) | 0.75 ± 0.19 (0.34 [0.30, 0.55]) | 0.99 |
| SUBSET THAT RECEIVED THE SAME OR LESS CONCOMITANT DIURETICS DURING THE 24 h AFTER THE START OF AMINOPHYLLINE (n= 24) | |||
| Urine outputa | 3.6 ± 0.5 (3.4 [1.9, 5.1]) | 4.4 ± 0.6 (3.5 [2.3, 5.5]) | 0.05 |
| BUNb | 24.0 ± 4.0 (14.5 [10.5, 33.5]) | 26.7 ± 5.1 (15.0 [10.0, 28.0]) | 0.15 |
| Creatinineb | 0.75 ± 0.18 (0.41 [0.32, 0.69]) | 0.81 ± 0.24 (0.37 [0.31, 0.66]) | 0.30 |
Both the mean plus/minus the standard error of the mean as well as the median (in parentheses) with the corresponding interquartile range [in brackets] are displayed for each value at each time point.
The p value was determined by the difference of the two values for each patient using the Wilcoxon Signed Rank test and was based on only the patients who had values recorded at both time points.
a Urine output is reported in terms of milliliters per kilogram per hour.
b The units for BUN and creatinine are milligrams per deciliter.