Table 5.

Sequencing technology error rates

Data set			Fractional error rate
Sample	#	Platform	Mismatches	Deletions	Insertions	Total
P. falciparum	1	Illumina MiSeq	0.0046	0.00021	0.00011	0.0049
	2	Ion Torrent PGM	0.0038	0.0090	0.0068	0.020
	3	Pacific Biosciences RS	0.0068	0.033	0.14	0.18
E. coli	4	Illumina MiSeq	0.0036	0.0000097	0.0000051	0.0037
	5	Ion Torrent PGM	0.0018	0.0053	0.0044	0.012
	6	Pacific Biosciences RS	0.0077	0.032	0.17	0.21
R. sphaeroides	7	Illumina MiSeq	0.0030	0.000018	0.0000089	0.0030
	8	Ion Torrent PGM	0.0014	0.0055	0.0037	0.011
	9	Pacific Biosciences RS	0.0076	0.029	0.16	0.20
Human	14	Illumina HiSeq	0.0030	0.00023	0.00017	0.0034
	15	Ion Torrent PGM	0.0060	0.0069	0.0057	0.019
	16	Complete Genomics	0.023	0.000099	0.000091	0.024

For a subset of the data sets in Table 2, we show the fractional rates of mismatch, deletion, and insertion, computed relative to coverage, inferred by comparison to the reference sequences. For human we note that bona fide differences between the sample and reference sequence were recorded as errors.