Methods	see STAY - Adults & STAY - Children
Participants	Combined data on Children and Adults aged 4 to 60 years with a history of one or more exacerbations in the past year
Interventions	see STAY - Adults & STAY - Children
Outcomes	see STAY - Adults & STAY - Children
Notes	Data presented for adults and children. P values based on ANOVA and changes from baseline calculated from Tables 1 & 2 in the primary publication. Standard Errors estimated from P values
Risk of bias
Item	Authors’ judgement	Description
Adequate sequence generation?	Yes	See STAY - Adults
Allocation concealment?	Unclear	See STAY - Adults
Blinding? All outcomes	Yes	See STAY - Adults
Incomplete outcome data addressed? All outcomes	Yes	See STAY - Adults