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. Author manuscript; available in PMC: 2014 Jun 12.
Published in final edited form as: Clin Sci (Lond). 2014 May;126(10):695–706. doi: 10.1042/CS20130294

Figure 2.

Figure 2

Effects of intracerebroventricular (ICV) administration of antisense oligodeoxynucleotides (AS-ODN) and scrambled oligodeoxynucleotides (Scr-ODN) on baseline renal sympathetic nerve activity (RSNA; A), mean arterial pressure (MAP; B), and heart rate (HR; C) in sham-operated (Sham) and chronic heart failure (CHF) rats. AS-ODN significantly decreased baseline RSNA, MAP, and HR (n = 7 for each group) over time. Values are means ± SE. *P < 0.05 compared with administration of Scr-ODN. From Zhu et al[32]. Reprinted with Permission from the American Journal of Physiology.