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AT1R protein expression in Cath.a neurons which were incubated with Ang II alone or in combination with either a mas receptor antagonist, A-779 or an AT1R receptor antagonist, losartan. Experiments were conducted with either a GFP adenovirus or human ACE2 adenovirus. ACE2 overexpression inhibited the upregulation of the AT1R in response to Ang II however this was not reversed by A-779. Data generated by Dr. Liang Xiao.
