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AT1R (A), GRK5 (B), p65 NF-κB (C) are increased in the PVN (solid bars) and RVLM (open bars) of CHF animals and normalized by ExT. GRK2 (D), another kinase implicated in regulating AT1R expression, is unchanged in the PVN during both CHF and ExT. *P<0.05 versus Sham-Sed. †P<0.05 versus CHF-Sed; n=5 to 7. From Haack et al[79].
