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. 2014 Feb 3;15(2):R28. doi: 10.1186/gb-2014-15-2-r28

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Copyright © 2014 Daniel et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Distance distribution between non-Alu editing sites and nearest edited Alu. The distance from random adenosines is shown as a broken red line. The distances were grouped in bins of 100, and their frequencies were plotted for a distance window of (a) 20 kb and (b) 2 kb. (c) Distance distribution plot with orientation, in bins of 10 nucleotides. Positive and negative distances indicate that the edited Alu is downstream or upstream of the (non-Alu) editing site. Blue bars: distance from editing sites to edited Alus. Red bars: distance from random adenosines to edited Alus. A significant tendency for Alus to be located downstream was observed (P = 3 × 10^-16). kb, kilobase; nt, nucleotide.