Table 1.

Selected top categories enriched in genes containing editing sites near an edited Alu

Category	Term	Count	Percentage a	P value	Fold enrichment	Benjamini b	False discovery rate
KEGG_PATHWAY	hsa04142; lysosome	7	2.9	9.32 × 10-9	46.1	8.02 × 10-7	1.01 × 10-5
PFAM	PF01352; KRAB box (Krueppel-associated box)	15	6.2	9.97 × 10-13	16.0	4.71 × 10-10	1.42 × 10-9
PANTHER_FAMILY	PTHR23224; zinc finger proteins	17	6.9	1.94 × 10-9	7.3	3.57 × 10-7	2.40 × 10-6
INTERPRO	IPR013087; zinc finger, C2H2-type/integrase, DNA-binding	17	6.9	3.22 × 10-8	6.0	7.15 × 10-6	4.56 × 10-5
SP_PIR_KEYWORDS	Alternative splicing	111	45.3	5.35 × 10-31	3.1	7.24 × 10-29	7.03 × 10-28
GOTERM_BP_ALL	GO:0045449; regulation of transcription	43	17.5	8.91 × 10-7	2.2	5.22 × 10-4	0.0014

^aPercentage of genes with the term of total genes in analyzed list; ^bBenjamini–Hochberg corrected P value for multiple comparisons.