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. 2014 Jul;86(1):52–61. doi: 10.1124/mol.114.092098

Fig. 5.

Fig. 5.

Desensitization decreased the amplitude and rate of rise of the current induced by photolysis of CYLE. (A) Example trace of an experiment where the current induced by CYLE is shown before and after desensitization with ME (30 µM). Arrows indicate the light flash. (B) Summarized results showing the inhibition and recovery of the amplitude of the current induced by CYLE. (C) Two superimposed traces of the current induced by CYLE before and after recovery from desensitization (10–20 minutes). (D) Summarized results showing the increase in the rise (time constant) before (C) and after recovery from desensitization (des) and before (C) or after application of β-CNA (CNA; 100 nM, 2 minutes). *P < 0.05 by paired Wilcoxon–Mann–Whitney rank sum test.