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. 2014 Jul;86(1):52–61. doi: 10.1124/mol.114.092098

Fig. 7.

Fig. 7.

CYLE-induced current is decreased by a receptor selective mechanism. (A) Example traces of the current induced by CYLE before (black) and after desensitization with OFQ (1 µM, 8–10 minutes, red). (B) Example traces of the current induced by CYLE (black) and in the presence of morphine (1 µM, 8–10 minutes, blue). (C) Summarized results measuring the time constant of the rate of rise. Experiments with OFQ and morphine were paired, and the control tau-On were combined for illustration. Statistics were done with a paired Wilcoxon–Mann–Whitney rank sum test (*P < 0.05). ns, not significant.