Table 2.
List of SNPs with an age-by-genotype interaction effect associated to GWAS hits.
| eQTL | Gene | Trait |
|---|---|---|
| Adipose | ||
| rs10516849 | MMRN1 | Parkinson's disease |
| rs10870077 | <NA> | Ulcerative colitis |
| rs12006032 | PRKACG | Chronic kidney disease |
| rs12523750 | MRS2 | Radiation response |
| rs12912744 | SERF2 | Lung cancer |
| rs17253722 | SHRM | Serum magnesium levels |
| rs17253722 | SHRM | Chronic kidney disease;renal function and chronic kidney disease |
| rs17253722 | SHRM | Eosinophilic esophagitis (pediatric) |
| rs17671591 | C5orf37 | LDL cholesterol |
| rs17671591 | C5orf37 | Quantitative traits |
| rs402710 | CLPTM1L | Lung cancer |
| rs402710 | CLPTM1L | Bladder cancer;pancreatic cancer |
| rs531676 | CRTAC1 | Metabolic syndrome |
| rs592229 | AGPAT1 | Menopause (age at onset) |
| rs592229 | AGPAT1 | Height |
| rs6143035 | CABLES2 | Colorectal cancer |
| rs6715570 | BARD1 | Neuroblastoma (high-risk) |
| rs708726 | RAB7L1 | Parkinson's disease |
| rs8049897 | DBNDD1 | Blond vs. brown hair color;freckles;redvs. non-red hair color;skin sensitivity to sun |
| rs8049897 | DBNDD1 | Black vs. red hair color;melanoma |
| rs9263871 | HCG27 | Protein quantitative trait loci |
| rs9263871 | HCG27 | Vitiligo |
| rs9263871 | HCG27 | CD4:CD8 lymphocyte ratio |
| rs9926577 | CNOT1 | QT interval |
| Skin | ||
| rs2305797 | RAB4B | Smoking behavior |
| rs1049337 | CAV1 | Electrocardiographic traits;PR interval |
| rs1042815 | HOXB2 | Primary tooth development (number of teeth) |