FIG 2.

Effect of DNase I on biofilm formation. S. mutans biofilms were grown in FMC with glucose (18 mM) and sucrose (2 mM) as the carbohydrate sources on hydroxylapatite discs vertically deposited in 24-well plates with inclusion of DNase I (DNase) for 5 and 24 h, respectively. Controls received the heat-inactivated enzyme (iDNase). Data presented here represent the averages (± standard deviations) from more than three independent sets of experiments, with an asterisk indicating statistical difference at P < 0.001 compared to the controls.