Skip to main content
. 2014 Jun;34(12):2264–2282. doi: 10.1128/MCB.01542-13

FIG 10.

FIG 10

PEA15 is epigenetically silenced due to promoter DNA methylation in patient-derived tumor samples. (A) RT-qPCR analysis of PEA15 mRNA levels in normal (n = 5) and primary tumor (n = 10) or metastatic tumor (n = 10) samples from colon, breast, or lung. The normal data point is an average of five samples. (B) Relative PEA15 methylation level analyses by Me-DIP in normal and primary tumor or metastatic tumor samples from colon, breast, or lung. The normal data point is an average of five samples. (C) Bisulfite sequencing analysis of PEA15 promoter methylation in normal and colon cancer samples. (D) Model.