FIG 4.
Ferret-adapted H7N1 is transmitted to CH and AC animals in a larger transmission study. Three ferrets received a pool of nasal wash fluid samples from line A p10 DI ferret (1 × 105 TCID50 of pooled virus). At 24 hpi, a CH and an AC ferret were introduced to the DI animals. Viral titers and percent weight losses of DI (A), CH (B), and AC (C) animals are shown. Red (blue or green) corresponds to one experimental cage setup consisting of three ferrets (one DI, one CH, and one AC) housed in the same isolator. Shown in parentheses is the proportion of ferrets that developed severe disease and were euthanized or succumbed to infection (†). N denotes neurological symptoms.