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Comparison of FLIP DEDs that are required for function
| Protein | Category and DED(s) required |
||
|---|---|---|---|
| Antiapoptosis | NF-κB | Anti-IRF3 | |
| MC159 | DED1 and DED2 (11) | DED1 (inhibit) (10) | DED1 or DED2 (1) |
| MC160 | No effect (8) | DED2 (inhibit) (12) | DED1 (1) |
| cFLIPL | DED1 and DED2 (15) | DED1 and DED2 (activate) (15) | Unknown |
| K13 | DED1 and DED2 (6) | DED1 (activate) (17) | Weak inhibitor (1) |
