TABLE 1.
D1-8 HAI and neutralization activities against representative influenza H3N2 virus strains
| Strain | HAI activitya (μg/ml) | Neutralization IC50 (μg/ml), mean ± SD |
|---|---|---|
| A/Hong Kong/8/1968 | 1.56 | 0.03 ± 0.02 |
| A/Victoria/3/1975 | 6.25 | 0.04 ± 0.003 |
| A/Los Angeles/2/1987 | 6.25 | 0.10 ± 0.05 |
| A/Shangdong/9/1993 | 12.5 | 0.66 ± 0.15 |
| A/Argentina/3779/1994 | 12.5 | 0.27 ± 0.12 |
| cab A/Sydney/5/1997 | 1.56 | 0.05 ± 0.03 |
| ca A/Panama/2007/1999 | 1.56 | 0.08 ± 0.03 |
| A/Wyoming/03/2003 | 0.4 | 0.03 ± 0.01 |
| ca A/California/7/2004 | 0.78 | 0.04 ± 0.01 |
| ca A/Wisconsin/67/2005 | 0.2 | 0.03 ± 0.003 |
| ca A/Perth/16/2009 | 0.2 | 0.01 ± 0.007 |
| A/Minnesota/11/2010 | >50 | 0.33 ± 0.14 |
| A/Indiana/10/2011 | >50 | 0.63 ± 0.13 |
a
HAI titers are expressed as the lowest concentrations of purified D1-8 that completely inhibited hemagglutination.
b
ca, cold adapted.