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Replication kinetics of the parental wild-type and mutant viruses. Confluent Vero cell monolayers were infected with each virus at either a low MOI/cell (0.2) (a) or a high MOI/cell (2.0) (b), and viral titers were obtained by plaque assay on FRT cells at different time points postinfection. HPI, h postinfection; error bars represent standard errors.
