Table 2.
Demographic characteristics and clinical symptoms of Parkinson's Disease (PD) patients who do and do not screen positive for dementia on the Chinese version of the Montreal Cognitive Assessment (MoCA-C) scale
| Screen positive for dementia (n=235) |
Screen negative for dementia (n=381) |
statistic | p-value | |
|---|---|---|---|---|
| Female (n [%]) | 123 (53.0%) | 118 (34.3%) | χ2=19.94 | <0.001 |
| Age (mean [sd]) | 69.3 (10.0) | 64.8 (10.6) | t=5.04 | <0.001 |
| Age of onset (mean [sd]) | 60.8 (11.4) | 58.4 (10.9) | t=2.54 | 0.012 |
| Years of education (median [IQR]) | 9 (6-12) | 12 (9-15) | Z=10.60 | <0.001 |
| Depression (HAMD score) (median[IQR]) | 13 (7-21) | 10 (6-16) | Z=3.67 | <0.001 |
| Depression (SDS score) (median [IQR]) | 31 (26-37) | 29 (25-35) | Z=2.90 | 0.004 |
| Anxiety (HAMA score) (median [IQR]) | 11 (7-17) | 9 (4-14) | Z=3.83 | <0.001 |
| Anxiety (SAS score) (median [IQR]) | 30 (26-34) | 28 (25-34) | Z=2.40 | 0.017 |
| Sleep (PDSS score) (median [IQR]) | 116 (98-131) | 121 (108-135) | Z=-3.80 | <0.001 |
| PD Non-motor symptoms (median [IQR]) | 12 (9-16) | 10 (6-14) | Z=4.58 | <0.001 |
| PD motor symptoms (score of Part III of UPDRS)(median[IQR]) | 34 (22-43) | 26 (24-28) | Z=7.57 | <0.001 |
| Hoehn and Yahr staging of PD (Part V of UPDRS) (median[IQR]) | 2.5 (2-3) | 2.0 (1.5-2.5) | Z=5.15 | <0.001 |
HAMD, Hamilton Depression Rating Scale
HAMA, Hamilton Anxiety Rating Scale
SDS, Zung self-rating Depression Scale
SAS, Zung self-rating Anxiety Scale
PDSS, Parkinson's disease Sleep Scale
UPDRS, United Parkinson's Disease Rating Scale