Table 1.
Immunohistochemical stain results
| Antibody/clone | Source | Result |
|---|---|---|
| Actin, smooth muscle/1A4 | Cell Marque, Rocklin, CA | Weak in some tumour cells |
| ALK-1/ALK01 | Ventana, Tucson, AZ | Negative in tumour cells |
| α-fetoprotein/polyclonal | Cell Marque | Negative in tumour cells |
| β-catenin/14 | Cell Marque | Negative in tumour cells |
| Calretinin/SP65 | Ventana | Negative in tumour cells |
| CD1a/EP3622 | Cell Marque | Negative in tumour cells |
| CD21/EP3093 | Cell Marque | Negative in tumour cells |
| CD23/SP23 | Ventana | Negative in tumour cells |
| CD30/Ber-H2 | Ventana | Negative in tumour cells |
| CD31/JC70 | Cell Marque | Negative in tumour cells |
| CD34/QBEnd/10 | Ventana | Negative in tumour cells |
| CD68/KP-1 | Ventana | Negative in tumour cells |
| CD163/MRQ-26 | Cell Marque | Negative in tumour cells |
| CEA/polyclonal | Cell Marque | Negative in tumour cells |
| Chromogranin/LK2H10 | Cell Marque | Negative in tumour cells |
| Cytokeratin | ||
| AE1/AE3/PCK26 | Ventana | Negative in tumour cells |
| CAM 5.2 | Ventana | Negative in tumour cells |
| CK7/SP52 | Ventana | Negative in tumour cells |
| CK20/SP33 | Ventana | Negative in tumour cells |
| Desmin/DE-R-11 | Ventana | Negative in tumour cells |
| Glypican-3/GC33 | Ventana | Negative in tumour cells |
| HSA (hepatocyte)/OCH1E5 | Cell Marque | Negative in tumour cells |
| Inhibin/R1 | Cell Marque | Negative in tumour cells |
| Ki-67/30–9 | Ventana | Positive in 5–10% of tumour cells |
| MART-1 (melan-A)/A103 | Cell Marque | Positive in tumour cells |
| Melanosome/HMB-45 | Ventana | Positive in tumour cells |
| PAX-8/MRQ-50 | Cell Marque | Negative in tumour cells |
| Renal cell carcinoma/PN-15 | Cell Marque | Negative in tumour cells |
| SOX-10/polyclonal | Cell Marque | Negative in tumour cells |
| Synaptophysin/MRQ-40 | Cell Marque | Negative in tumour cells |
| TTF-1/V9 | Ventana | Negative in tumour cells |
ALK-1: anaplastic lymphoma kinase-1, a tyrosine receptor kinase expressed by neoplastic cells in anaplastic large cell lymphoma, inflammatory myofibroblastic tumor and other neoplasms; AE1: Clone name of antibody to acidic cytokeratins 10, 14, 15, 16 and 19; AE3: Clone name of antibody to basic cytokeratins 1, 2, 3, 4, 5, 6, 7 and 8; CAM 5.2: Clone name of antibody to cytokeratins 8 and 18; CEA: carcinoembryonic antigen; HMB-45, human melanoma black-45; PCK26: Clone name of antibody to cytokeratins 5 and 8; MART-1, melanoma antigen recognised by T Cell-1; MRQ-26: Clone name of antibody to CD163, scavenger protein expressed by cells of monocytes/macrophage lineage; MRQ-40: Clone name of antibody to synaptophysin; MRQ-50: Clone name of antibody to PAX-8 protein; EP3622: Clone name of antibody to CD1a; EP3093: Clone name of antibody to CD21; SP23: Clone name of antibody to CD23; SP33: Clone name of antibody to cytokeratin 20; SP52: Monoclonal antibody to cytokeratin 7; SP65: Clone name of antibody to calretinin, a protein expressed by normal and neoplastic mesothelial cells; Ber-H2: Clone name of antibody to CD30; HSA: Hepatocyte specific antigen present in normal and neoplastic hepatocytes; OCH 1E5: Clone name of antibody to HAS; PAX-8: Transcription factor encoded by the PAX8 (paired box 8) gene, expressed in neoplasms of the kidney, upper urinary tract, thyroid and Müllerian system; SOX-10: Transcription factor encoded by the SRY (sex determining region Y) box 10 gene, involved in the regulation of embryonic development and cell fate, expressed in melanoma cells; TTF-1: Thyroid transcription factor, expressed in normal and neoplastic cells of the thyroid and lung.