Figure 6.

The interface between different organisms, and their physiologies, basically is ecological. The quantity of these interactions as well as their impact on physiologies increases with the number of organism types involved. With phage therapy, this includes three distinct species. (1) the patient, host, subject, or body that is experiencing a bacterial infection; (2) the infecting bacterial pathogen; and (3) the bacterial virus, a.k.a., phage or bacteriophage that is being used to treat the bacterial infection. Phage therapy pharmacology lies at the interface of these three components and thus inherently straddles both ecological and physiological considerations (with that confluence indicated by the star but not limited to the star). Since physiologies change with varying infection conditions as well as treatment approaches, including in terms of physiological adaptation to these changing conditions, phage therapy pharmacology can be viewed as being inherently eco-physiological.