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. 2014 Mar 21;15(4):R62. doi: 10.1186/gb-2014-15-4-r62

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Copyright © 2014 Shu et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Promoter cis-regulatory sequences affect local H3.3 incorporation. (A-C) Metagene plots of H3.3 signals across gene bodies (blue bar) between -3 kb and +3 kb for genes with promoters that carry TATA elements (A), GA elements (B) or neither TATA nor GA elements (coreless) (C). Genes were first grouped according to transcript abundance, and genes with promoters of each type are presented separately. (B) H3.3 signals at promoters with GA elements (red) or promoters of the top 25% most strongly expressed genes (blue).