Table 8.
Dataset | Median ESE | Median non-ESE | % Difference | P two-sided |
---|---|---|---|---|
A | ||||
RESCUE |
0.03 |
0.036 |
-16.7 |
1.60E-28 |
PESE |
0.031 |
0.036 |
-13.9 |
7.10E-27 |
ESR |
0.031 |
0.038 |
-18.4 |
8.30E-30 |
Ke-ESE400 |
0.04 |
0.032 |
25 |
6.20E-30 |
Ke-ESE |
0.036 |
0.03 |
20 |
1.20E-31 |
INT3.400 |
0.029 |
0.035 |
-17.1 |
1.30E-22 |
INT3 |
0.029 |
0.035 |
-17.1 |
9.60E-25 |
INT2.400 |
0.031 |
0.036 |
-13.9 |
2.10E-24 |
INT2 |
0.032 |
0.036 |
-11.1 |
4.10E-23 |
B | ||||
RESCUE |
0.03 |
0.031 |
-3.2 |
2.70E-18 |
PESE |
0.031 |
0.033 |
-6.1 |
7.80E-18 |
ESR |
0.031 |
0.034 |
-8.8 |
2.30E-26 |
Ke-ESE400 |
0.04 |
0.036 |
11.1 |
1.60E-26 |
Ke-ESE |
0.036 |
0.035 |
2.9 |
7.30E-18 |
INT3.400 |
0.029 |
0.034 |
-14.7 |
4.20E-24 |
INT3 |
0.029 |
0.035 |
-17.1 |
5.70E-27 |
INT2.400 |
0.031 |
0.035 |
-11.4 |
1.20E-27 |
INT2 | 0.032 | 0.035 | -8.6 | 1.80E-28 |
Statistics are from a paired test in which we compare the proportion of sites with a SNP within an ESE with sites equidistant from an exon junction but (a) not in an ESE or (b) in a pseudoESE, using a Wilcoxson paired test. Percentage difference is defined as (Median for ESE -Median for non-ESE)/Median for non-ESE. All tests are significant after Bonferonni correction (for consistency the P values are shown in bold).