Table 3.

Ontology enrichment analysis for age-associated differentially methylated regions

GO term	Description	-log10 binomial P-value
GO:0048513	Organ development	17.68
GO:00048869	Cellular development process	15.59
GO:0030154	Cell differentiation	15.33
GO:0010033	Response to organic substance	14.47
GO:0009887	Organ morphogenesis	14.00
GO:0006359	Regulation of transcription from RNAs pol III promoter	9.66
GO:0000975	Regulatory region DNA binding	8.73
GO:0044212	Transcription regulatory region DNA binding	8.00
GO:0045945	Positive regulation of transcription from RNA pol III promoter	7.51
GO:0048598	Embryonic morphogenesis	6.80
GO:0016480	Negative regulation of transcription from RNA pol III promoter	6.67
GO:0003205	Cardiac chamber development	5.71
GO:0030326	Embryonic limb morphogenesis	4.4
GO:0060173	Limb development	3.82
GO:0035108	Limb morphogenesis	3.62
GO:0048546	Digestive tract morphogenesis	3.10

Gene Ontology (GO) terms significant at an adjusted P-value <0.05 [81] are shown.