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Kinetic parameters of the resistant (119 F) and susceptible (L119) GSTe2 alleles
| V max (DDE μmol.min −1 .mg −1 ) | K m (μM DDT) | Kcat (s −1 ) | Kcat/ K m (μM −1 .s −1 ) | |
|---|---|---|---|---|
| 119 F-GSTe2 |
60.8 ± 7.2 |
149.6 ± 39.6 |
47312 ± 5297 |
316.3 |
| L119-GSTe2 | 3.75 ± 0.26 | 34 ± 5.9 | 3129 ± 222.6 | 92.0 |
Three independent assays were performed for both alleles and the results show mean ± standard deviation.
