Table 4. Summary of Bland-Altman plot for measurements of each retinal layer.
The higher quality scan was always analyzed first so that any bias due to image quality could be detected.
| Control n = 48 |
Nystagmus n = 49 |
||||||
|---|---|---|---|---|---|---|---|
| Retinal Layer | Mean (μm) (SD) | 95% Limits of agreement | Bias (p Value) | Retinal Layer | Mean (μm) (SD) | 95% Limits of agreement | Bias (p Value) |
| CMT n = 48 | 192.100 (24.957) | −3.8 to 2.3 | 0.291* (0.044) | CMT n = 48 |
240.908 (61.075) | −7.5 to 4.1 | −0.066 (0.656) |
| NFL n = 1 | ---------- | ---------- | ---------- | NFL n = 26 |
9.479 (3.962) | −4.9 to 0.2 | 0.058 (0.777) |
| GCL n = 1 | ---------- | ---------- | ---------- | GCL n = 26 |
25.864 (8.288) | −4.3 to 6.4 | 0.092 (0.653) |
| IPL n = 4 | ---------- | ---------- | ---------- | IPL n = 29 |
30.552 (9.455) | −4.6 to 4.2 | 0.139 (0.472) |
| GCL and IPL n = 1 | ---------- | ---------- | ---------- | GCL and IPL n = 28 |
53.959 (20.355) | −6.4 to 4.4 | 0.290 (0.134) |
| INL n = 4 | ---------- | ---------- | ---------- | INL n = 28 |
53.959 (20.355) | −6.2 to 4.4 | −0.615* (0.000) |
| OPL n = 4 | ---------- | ---------- | ---------- | OPL n = 28 |
18.893 (8.069) | −5.3 to 1.4 | −0.609* (0.001) |
| ONL n = 47 | 96.049 (18.004) | −3.2 to 3.4 | 0.139 (0.350) | ONL n = 47 |
90.332 (22.557) | −5.2 to 3.8 | 0.080 (0.592) |
| IS n = 45 | 29.340 (5.234) | −3.5 to 0.8 | −0.700 (0.648) | IS n = 38 |
26.871 (4.503) | −0.2 to 4.0 | −0.830 (0.620) |
| ONL and IS n = 45 | 125.811 (20.261) | −3.9 to 2.6 | 0.196 (0.197) | ONL and IS n = 42 |
118.081 (22.498) | −6.7 to 5.4 | 0.060 (0.704) |
| OS n = 46 | 37.409 (8.031) | −1.0 to 2.8 | 0.089 (0.556) | OS n = 42 |
32.607 (7.664) | −1.3 to 3.5 | 0.402* (0.008) |
| RPE n = 48 | 27.325 (5.091) | −0.9 to 2.9 | 0.210 (0.152) | RPE n = 49 |
25.753 (5.807) | −1.7 to 2.2 | −0.117 (0.424) |
| OS and RPE n = 48 | 62.575 (13.377) | −2.5 to 3.1 | 0.484* (0.000) | OS and RPE n = 49 |
53.898 16.927 | −2.9 to 2.1 | 0.647* (0.000) |
n = sample size; CI = confidence interval; CMT = central macular thickness; NFL= nerve fiber layer; GCL= ganglion cell layer; IPL= inner plexiform layer; INL= inner nuclear layer; OPL= outer plexiform layer; ONL= outer nuclear layer; ELM= external limiting membrane; IS = inner segment of photoreceptors; OS = outer segment of photoreceptors; RPE= retinal pigment epithelium; SD = standard deviation;
*
= significant at a value p < 0.05