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. Author manuscript; available in PMC: 2014 Jun 12.
Published in final edited form as: Transl Stroke Res. 2012 Apr 12;3(0 1):102–112. doi: 10.1007/s12975-012-0161-1

Table 1.

Subject characteristics

AD (ADNI)
CAA-related ICH (MGH)
ROS/MAP
Cases Controls Cases Controls
No. of subjects 308 215 175 324 730
Age (Mean, SD) 75.5 (7.7) 75.9 (5.5) 76.4 (8.2) 74.1 (8.3) 81.2 (6.8)
Sex (% male) 42 45 46 45 37
History of hypertension (%) 50 45 55 49 58
Ever smoker (%) 39 36 41 35 27
Alcohol abuse (%) 5 2 7 3 3
APOE ε2 (MAF) 0.21 0.07 0.16 0.07 0.082
APOE ε4 (MAF) 0.32 0.14 0.25 0.12 0.151

AD=Alzheimer's disease, CAA=cerebral amyloid angiopathy, MAF=minor allele frequency, SD=standard deviation