Table 1.
AD (ADNI) |
CAA-related ICH (MGH) |
ROS/MAP | |||
---|---|---|---|---|---|
Cases | Controls | Cases | Controls | ||
No. of subjects | 308 | 215 | 175 | 324 | 730 |
Age (Mean, SD) | 75.5 (7.7) | 75.9 (5.5) | 76.4 (8.2) | 74.1 (8.3) | 81.2 (6.8) |
Sex (% male) | 42 | 45 | 46 | 45 | 37 |
History of hypertension (%) | 50 | 45 | 55 | 49 | 58 |
Ever smoker (%) | 39 | 36 | 41 | 35 | 27 |
Alcohol abuse (%) | 5 | 2 | 7 | 3 | 3 |
APOE ε2 (MAF) | 0.21 | 0.07 | 0.16 | 0.07 | 0.082 |
APOE ε4 (MAF) | 0.32 | 0.14 | 0.25 | 0.12 | 0.151 |
AD=Alzheimer's disease, CAA=cerebral amyloid angiopathy, MAF=minor allele frequency, SD=standard deviation