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. 2011 Sep 21;302(1):C296–C306. doi: 10.1152/ajpcell.00177.2011

Fig. 1.

Fig. 1.

Inhibition of outward K+ current of the outer hair cells (IK) by 4-AP and low extracellular Cl−. Membrane current was recorded with 200-ms pulses to potentials between −90 and 50 mV from a holding potential of −40 mV. The waveforms of the 4-AP- and Cl−-sensitive currents were determined by subtraction of control currents. A: a, control; b, 100 μM 4-AP; c, 100 μM 4-AP-sensitive current; d, current-voltage relationship of IK for control (□), 100 μM 4-AP (○), and 100 μM 4-AP-sensitive current (▾) (n = 3). B: a, control; b, 5 mM Cl−; c, 5 mM Cl−-sensitive current; d, current-voltage relationship of IK for control (□), 5 mM Cl− (○) and 5 mM Cl−-sensitive current (▾) (n = 5). C: a, control; b, 100 μM 4-AP; c, 100 μM 4-AP + 5 mM Cl−; d, current-voltage relationship of IK for control (□), 100 μM 4-AP (◊), and 100 μM 4-AP + 5 mM Cl− (▾) (n = 3).