Table 7.
Adverse events reported in five or more patientsa
| Adverse event | Patients, n (%); N = 52 |
|---|---|
| Any adverse event | 49 (94.2) |
| Most common adverse events | |
| nausea | 33 (63.5) |
| vomiting | 18 (34.6) |
| fever | 13 (25.0) |
| diarrhoea | 12 (23.1) |
| anorexia | 11 (21.2) |
| asthenia | 11 (21.2) |
| abdominal pain | 9 (17.3) |
| respiratory disorder | 8 (15.4) |
| pain | 6 (11.5) |
| insomnia | 6 (11.5) |
| chest pain | 5 (9.6) |
| peripheral oedema | 5 (9.6) |
| weight loss | 5 (9.6) |
| tinnitus | 5 (9.6) |
| Serious adverse events | 29 (55.8) |
| related to study drug (see the text for details) | 12 (23.1) |
aIncludes all patients with either lung or extrapulmonary infection.