Table 1.
Stereological analysis of wounds in diabetic animals
| Parameter | CACs (OPN) + Collagen | CACs + Collagen | Collagen | Untreated |
|---|---|---|---|---|
| Wound volume (mm3) |
13.2 ± 5.1* |
14.1 ± 3.5 |
17.4 ± 3.6#* |
12.03 ± 3.69 |
| Total volume of inflammatory cells (mm3) |
2.37 ± 0.97# |
3.01 ± 1.16# |
3.21 ± 0.91# |
1.39 ± 0.5 |
| Surface density of blood vessels in wound (mm-1) |
22.4 ± 9.3# |
21.6 ± 4.34# |
25.6 ± 5.8# |
11.1 ± 5 |
| Surface area of blood vessels (mm2) |
306.3 ± 178 |
330.5 ± 20# |
442 ± 112# |
146 ± 116 |
| Length density of blood vessels in wound (mm-2) |
6,212 ± 1,424# |
6,534 ± 1,589# |
7,575 ± 1,610# |
4,116 ± 1093 |
| Total length of blood vessels in wound (mm) |
81,678 ± 35,117 |
90,490 ± 26,997# |
131,220 ± 34,187# |
49,337 ± 51595 |
| Radial diffusion distance (μm) |
7.29 ± 0.9# |
7.16 ± 0.1# |
6.56 ± 0.6# |
9.05 ± 0.15 |
| Vessel diameter (μm) | 1.8 ± 0.47# | 1.76 ± 0.46 | 1.74 ± 0.3 | 1.35 ± 0.38 |
Stereology analyzed by ANOVA followed by Fisher’s pairwise comparison, mean ± standard deviation, n = 8, *P <0.05 compared to * in the same row, #P <0.05 compared to untreated wound.