Table 1.
Methodologies for computing the equivalent dose used in eight clinical calculators from seven radiotherapy centers. The median dose, average dose, and standard deviation are given in Gy. For the standard deviation, absolute and relative modes (σ/average) were used. Bold font is used to represent values >5%.
| Treatments | Organs at risk | Target volumes | |
|---|---|---|---|
| Spinal cord |
Prostate (metastasis) |
||
| 10 × 3 Gy | Median | 37.50 | 36.65 |
| Average ± 95% CI | 37.8 ± 1.2 | 36.6 ± 1.9 | |
| Stand dev | 1.71/4.5% | 2.87/7.8% | |
| Spinal cord |
Breast (metastasis) |
||
| 10 × 3 Gy | Median | 37.50 | 35.57 |
| Average ± 95% CI | 37.8 ± 1.2 | 35.97 ± 1.4 | |
| Stand dev | 1.71/4.5% | 2.06/5.7% | |
| Spinal cord |
Prostate (metastasis) |
||
| 1 × 8 Gy | Median | 20.00 | 14.90 |
| Average ± 95% CI | 19.1 ± 2.3 | 15.9 ± 3.2 | |
| Stand dev | 3.38/17.7% | 4.72/29.6% | |
| Brain |
Breast (metastasis) |
||
| 10 × 3 Gy | Median | 37.50 | 35.57 |
| Average ± 95% CI | 37.5 ± 0.9 | 35.9 ± 1.4 | |
| Stand dev | 1.26/3.4% | 2.03/5.6% | |
| Spinal cord |
Prostate (metastasis) |
||
| 1 × 8 Gy (1 month gap time) 1 × 8 Gy | Median | 33.30 | 21.50 |
| Average ± 95% CI | 33.6 ± 4.0 | 24.04 ± 6.8 | |
| Stand dev | 5.78/17.2% | 9.76/40.6% | |
| Pericardium |
Lung (metastasis) |
||
| 5 × 4 Gy | Median | 30.90 | 27.07 |
| Average ± 95% CI | 33.7 ± 5.9 | 28.9 ± 3.6 | |
| Stand dev | 8.47/25.1% | 5.14/17.8% | |
| Oral mucosa |
Oropharynx |
||
| 20 × 2 Gy (1 week gap time) 10 × 2 Gy | Median | 57.95 | 57.95 |
| Average ± 95% CI | 58.1 ± 0.5 | 57.6 ± 1.9 | |
| Stand dev | 0.66/1.14% | 2.76/4.8% | |
| Oral mucosa |
Oropharynx |
||
| 22 × 1.8 Gy (bi-fractionated) | Median | 41.95 | 41.70 |
| Average ± 95% CI | 41.0 ± 1.6 | 41.7 ± 2.2 | |
| Stand dev | 2.32/5.6% | 3.12/7.5% | |
| Rectum |
Prostate |
||
| 25 × 1.8 Gy then 15 × 2 Gy | Median | 72.58 | 72.75 |
| Average ± 95% CI | 72.6 ± 0.4 | 72.6 ± 0.7 | |
| Stand dev | 0.54/0.7% | 1.00/1.37% | |
| Lung |
Breast |
||
| 20 × 2.5 Gy (4 fraction/week) | Median | 55.58 | 53.50 |
| Average ± 95% CI | 55.0 ± 1.1 | 53.5 ± 1.2 | |
| Stand dev | 1.59/2.9% | 1.71/3.2% | |
| Optic chiasma |
Glioblastoma |
||
| 4 × 4.5 Gy (2 week gap time) 4 × 4 Gy | Median | 50.25 | 42.15 |
| Average ± 95% CI | 49.9 ± 2.7 | 43.1 ± 2.8 | |
| Stand dev | 3.96/7.9% | 4.07/9.4% | |
| Skin (early) |
Breast |
||
| 28 × 1.8 Gy (1 week gap time) | Median | 46.65 | 46.36 |
| Average ± 95% CI | 46.7 ± 0.6 | 46.5 ± 0.8 | |
| Stand dev | 0.90/1.9% | 1.13/2.4% | |