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Toxicity profile in two groups.
| Parameters | Experimental group (n = 52) | Control group (n = 46) | ||
|---|---|---|---|---|
| Grade | 1-2 | 3-4 | 1-2 | 3-4 |
| Neutropenia | 12 | 40 | 14 | 0 |
| Liver damage | 6 | 0 | 12 | 3 |
| Renal damage | 0 | 0 | 0 | 0 |
| Cardiac damage | 0 | 0 | 0 | 0 |
| Gastrointestinal symptom | 5 | 0 | 4 | 0 |
| Oral ulcer | 0 | 0 | 7 | 0 |
Neutropenia was higher in experimental group (P = 0), while liver damage is higher in control group (P = 0.0112).
