Fig. 4.

Forest plot of survival by patient subgroup. Red line represents the hazard ratio (HR) of the ITT population and the dashed line represents an HR of 1. The squares represent the HR and sample size for each subgroup, where the area of the square is proportional to the subgroup sample size. CI, confidence interval; ECOG PS, Eastern Cooperative Oncology Group performance status; HR, hazard ratio; IPSS, International Prognostic Scoring System; ITT, intention-to-treat; PET-MF, post-essential thrombocythaemia myelofibrosis; PMF, primary myelofibrosis; PPV-MF, post-polycythaemia vera myelofibrosis.