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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: J Immunol. 2013 Jun 24;191(3):1453–1464. doi: 10.4049/jimmunol.1203318

Figure 7. Levels of Th1, Th2 and iBALT-associated chemokines in wild-type and IL-6-/- mice following endo-tracheal administration with Ad-mOSM.

Figure 7

C57Bl/6- and IL-6-/- mice were inoculated with Ad-del70, Ad-mOSM adenovirus or PBS (un-infected). BAL fluid was collected 7 days after infection to quantify protein levels of Th1-, Th2 cytokines and iBALT-associated chemokines. (A) Protein concentration of the typical Th2 cytokines: IL-4, IL-5 and IL-10 (top panels) and typical Th1 cytokines: TNFα and IL-12 (bottom panels) was determined in BAL fluids by luminex bead array analysis as described in Materials and Methods. (B) Protein levels of homeostatic chemokines (CCL20, CXCL13, CCL21) in BAL fluid were measured by ELISA. Results are showed as the means ± SEMs, n= 4 mice per group. Data shown is representative of at least two separate experiments.